Some of the common Ozempic side effects are nausea, vomiting, diarrhea, stomach pain, constipation, upset stomach, heartburn, burping, gas, bloating, loss of appetite, runny nose or sore throat, stomach flu symptoms, headache, dizziness, tiredness and low blood sugar (in people with type 2 diabetes).
Stomach or gastrointestinal Ozempic side effects are more common but they are mild and go away in a few weeks in most people and would not interfere with long-term treatment. Stomach issues can be more common with higher doses.
The most common gastrointestinal Ozempic side effect is nausea, which occurs in about 15% to 20% of people.
- Others include 5% to 9% vomiting, 8% diarrhea, 6% to 7% stomach-area pain, and 3% to 7% constipation.
- These side effects occur at higher rates than the placebo-treated groups (receiving an inactive treatment).
More patients receiving Ozempic 0.5 mg (3.1%) and 1 mg (3.8%) discontinue their treatment due to stomach issues than the patients who are receiving placebo (0.4%).
Stomach issues generally occur at the beginning of treatment and if your dose is increased too quickly. Because of this, your healthcare provider slowly increases your dose every 4 weeks as needed until you reach your targeted dose. You can take Ozempic with or without meals.